Modern explanation of acupuncture effect According to modern scientific studies treatment effect of acupuncture mainly takes place due to the following reasons: 1. Human body consists of intracellular and extracellular compartments. By other words, cells (No 1 on corresponding picture), comprizing living tissue, are surrounded by extracellular substance, called interstitium (No2). Continuous transport of material and signals between these two compatrtments is actually energy flow. As far as this energy flow is fluent, the exchange process is uninterrupted and balance between extra and intracellular compartments is preserved and homeostasis is maintained. In many situations this energy transport occurs through special gates on the cell membrane, which open due to changes in electric potential differences between two sides of membrane. In case of problem with opening of these gates the flow of energy is blocked and contact of the cells with interstitium is interrupted, which leads to formation of disease signs. So the formula FREE ENERGY FLOW = HEALTH is equally applicable both in Western and Chinese medicines. 2. The only tissue, which can be found in any part of human body, is connective tissue. Recent research demonstrated that apart from having structural characteristics, connective tissue can both generate and convey electric impulse like semiconducting material. Insertion of needle into connective tissue causes the generation of local piezoelectric effect, which propagates through special ways to problem area, resolves electropotential blockage, reopens the gates and restores free energy flow through cell membrane